Recent advances in carrier mediated nose-to-brain delivery of pharmaceutics
نویسندگان
چکیده
منابع مشابه
Nose to Brain Drug Delivery: A Recent Update
Drugs used to treat brain or central nervous system disorder suffer from shortfall of absorption and reaching brain due to blood brain barrier and cerebro spinal fluid barrier. Intra nasal administration of brain targeted drug delivery system is gaining popularity to circumvent blood brain barrier and enhance drug availability in brain. It also shows promising reduction of systemic adverse effe...
متن کاملNose to Brain Drug Delivery: A Recent Update
Drugs used to treat brain or central nervous system disorder suffer from shortfall of absorption and reaching brain due to blood brain barrier and cerebro spinal fluid barrier. Intra nasal administration of brain targeted drug delivery system is gaining popularity to circumvent blood brain barrier and enhance drug availability in brain. It also shows promising reduction of systemic adverse effe...
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Phytocompounds have been used in medicine for decades owing to their potential in anti-inflammatory applications. However, major difficulties in achieving sustained delivery of phyto-based drugs are related to their low solubility and cell penetration, and high instability. To overcome these disadvantages, nanosized delivery technologies are currently in use for sustained and enhanced delivery ...
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Drug delivery to the Central Nervous System (CNS) in treatment of CNS related disorders is very complicated and challenging. Although some neuropharmaceutical agents have great potential for treating CNS disorders, major challenge to CNS drug delivery is the Blood Brain Barrier (BBB), which limits the access of drugs to the brain. Progress in brain drug delivery has lagged behind other areas be...
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ژورنال
عنوان ژورنال: European Journal of Pharmaceutics and Biopharmaceutics
سال: 2018
ISSN: 0939-6411
DOI: 10.1016/j.ejpb.2018.05.009